Dedicated to develop novel stem cell therapies to treat chronic diseases
There is a large unmet clinical need for stem cell treatment of chronic diseases, however stem cell populations including Adipose Derived Regenerative Cells (ADRCs) are heterogenous and our understanding of their in vivo origin and properties is incomplete. Stem cell treatments hold the promise of modifying or even curing diseases, however the current regulatory environment need strong data for approval.
We have discovered that one specific cell type, dubbed ‘blue cells’ has remarkable clinical effects in multiple diseases. In phase 1 trials, we have found that a single injection of the patients own ADRCs reversed erectile dysfunction in prostatectomized men and alliviated lympehedema in women after breast cancer operation. Only the blue cells correlated with clinical efficiency.
Our mission is to translate knowledge from basic science and animal experiments into novel treatments for chronic diseases including erectile dysfunction and lymphedema using specific stem cell types including the so-called blue cells that are a subset of ADRCs with angiogenic and regenerative properties.
Our goal is to introduce Blue Cell treatment for Erectile Dysfunction and Lymphedema as the gold standard in hospitals and clinics to make the treatments available to patients worldwide. We shall develop Blue Cell products and methodologies in two steps: first, we will treat the patients with their own Blue Cells to obtain facilitate regulatory approval, and secondly, we shall use knowledge and data from step 1 to develop an allogenic therapy product.
To develop new enzymes and equipment for blue cell isolation in order to increase efficiency and to reduce the treatment price by a factor of 2-3
To develop a GMP compliant cell culture of the blue cells isolated from the patients own adipose tissue
To establish reproducibility, safety, efficacy and adverse effects of autologous blue cells for treatment of erectile dysfunction and lymphedema
To develop a GMP compliant blue cell culture for allogenic treatment
“The safety of using the patients own Blue Cells will increase acceptance for large scale uptake.”
SOREN SHEIKH | CO-FOUNDER
The company is a spin-out from University of Southern Denmark and Odense University Hospital. The effort to get ADRC treatments to the patients has been supported by 25 mio. DKK and 5 mio. DKK Grand Solution grants from the Danish Innovation Fund to SPS and the team at Odense University Hospital and University of Southern Denmark. In addition, Blue Cell Therapeutics’ application for the Eurostars program was ranked 17 out of 400 applications in EU, resulting in a 600.000 EUR grant. Novozymes is a partner in both the Innovation Fund and Eurostar projects.